Is the wine 如果后面已经有and的话就很难直接再家of或from了。要看语境。Is the wine from:这酒是从。。。?Is the wine of:这酒是[某某品牌,地方的]?说Is the一般是问句。如果想说这酒是从某某国家来的:This/the wine is from。。。如果是说哪个品牌/农庄:This/the wine is of 。。。make/brand。